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[email protected]First, urea was cyclized with 1,1,3,3-Tetramethoxypropane (Sigma-Aldrich) under acidic conditions to obtain 2-hydroxypyrimidine (2HP). 2HP was then coupled with 2,3,4,5,6-Pentafluorobenzyl bromide (Sigma-Aldrich) to yield a derivative that, upon negative ion chemical ionization gas-chromatography mass spectrometry, yields a negatively charged 2 ...
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